Faculty

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Allard, Jun Mathematical modeling of cell mechanics; How forces are used by cells for cell-cell communication, actin-based crawling, internal trnasport and cytoskeleton dynamics; Nonlinear partial differential equations, stochastic simulation and Bayesian statistics.
Allison, Steven Microbial enzymes, theoretical, and biogeochemistry.
Anderson, Bogi Transcriptional regulation in normal and diseased epithelia
Andricioaei, Ioan Interface of structural molecular biology and physical chemistry
Aphasizhev, Ruslan Molecular biology of trypanosomes, mitochondrial RNA editing, mechanisms of template-independent nucleotide recognition and transfer
Arora, Kavita Drosophila development, TGF-beta signal transduction, cell signaling
Atwood, Scott Cell fate decisions in skin cancer, skin and hair follicle development, and stem cells
Baldi, Pierre Artificial Intelligence: Automated Reasoning / Machine Learning / Data Mining / Large-Scale Data Analysis: Information Access & Management / Computational Biology / Bioinformatics / Systems Biology
Bardwell, Lee Use of molecular biology, biochemistry, genetics, cell biology and math/computation to study fundamental questions of cell signaling and regulation
Bennett, Albert Evolutionary and comparative physiology
Blumburg, Bruce Molecular embryology, molecular biology, developmental biology, functional genomics, endocrinology, pharmacology, high-throughput screening
Botvinick, Elliot The relationship between mechanical stresses on cells and molecular signaling, or cellular mechanotransduction. Investigation of the role of the glycocalix in the transduction of fluid shear stress at the wall of blood vessels, and is constructing an instrument to study the scale of mechanical induction of vascular inflammation.
Briscoe, Adriana Molecular evolution, color vision, wing color, behavior
Brody, Jim Single molecule dynamics, bioinformatics, functional genomics, surface plasmon resonance
Calof, Anne Systems biology of stem cells and human genetic disease
Chen, Long Theoretical analysis and practical application of Adaptive Finite Element Methods (AFEMs)
Cho, Ken Growth factor signaling and functional genomics in Xenopus and zebrafish, stem cell research and diabetes, Bioinformatics and functional genomics, Veterbrate embryology and growth factor signaling
Cinquin, Olivier Systems biology of cell differentiation.
Cocco, Melanie NMR spectroscopy, DNA-binding proteins, membrane proteins, cancer
Collins, Philip Nanomaterial Synthesis  & Characterization, Nanocircuit Behaviors, Single Molecule Circuits
Cooper, Dan Effect of exercise on gene and protein expression of key inflammatory and growth mediators in peripheral blood mononuclear cells in health children
Cramer, Karina Molecular and cellular signals that assemble neural circuitry
Dai, Xing Role of the regulatory proteins Ovo in germ cell and epidermal differentiation
Dennin, Michael Biological physics, Langmuir monolayers, Foams
Digman, Michelle Fluorescence dynamics imaging
Downing, Tim Epigenomic control through cell-material interactions
Emerson, J.J. Evolution of genetic novelty: copy number variation, gene duplication, sex chromosome evolution and the evolution of gene expression.
Enciso, German Computational and systems biology, including modeling of signal transduction, gene and protein networks, and stochastic systems
Fowlkes, Charless Artificial Intelligence: Automated Reasoning / Machine Learning / Data Mining; Bio-Medical Informatics / Computational Biology
Frank, Steve Evolutionary genetics, host-parasite interactions, development of mathematical, computational and conceptual models to study complex phenotypes
Ganesan, Anand Systems level approaches to regulatory pathways in skin and melanoma
Gardiner, Dave Limb regeneration; dedifferentiation; pattern formation
Gaut, Brandon Population genetics, molecular evolution, genome evolution
Gershon, Paul Nucleic acid-protein interactions and molecular dynamics, catalytic mechanisms, proteomics, virion structure
Gratton, Enrico Design of new fluorescence instruments, protein dynamics, hydration of proteins, and I.R. spectroscopy of biological substances
Grosberg, Anna Cardiovascular modeling: development and function at the cellualr, tissue and organ level
Gross, Steve Biophysics of molecular motors and intracellular transport 
Guidotti, Patrick Partial Differential Equations and Applied (Functional) Analysis
Gutman, George Structure and evolution of potassium channels and immunoglobulin super-family genes
Hatfield, Wes Global gene regulation and mechanisms of pathogenesis in Escherichia coli K12 and pathogenic bacteria, Computational and genomic methods 
Haun, Jered Nanothechnology and biomarkers of cancer and atherosclerosis
Hayes, Wayne Large-Scale Data Analysis: Information Access & Management / Databases / Information Infrastructure / Bio-Medical Informatics / Computational Biology
Hertel, Klemens Mechanisms of pre-mRNA splicing and the function of splicing enhancers  in exon definition, Regulation of pre-mRNA splicing and human genetic diseases, The coupling of transcription and pre-mRNA splicing
Huang, Lan Biological mass spectrometry/proteomics, ubiquitin-proteasome degradation pathways, protein complexes, posttranslational modifications, protein-protein interaction
Hughes, Chris 3D tissue modeling, angiogenesis, tumor microenvironment
Hui, Elliot Microengineered tissue models, dynamics of cell-cell signaling, soluble factor gradients
Ihler, Alexander Artificial Intelligence: Automated Reasoning / Machine Learning / Data Mining
Johnson, Wesley Developing Bayesian statistical methods for biostatistical and epidemiologic applications
Kaiser, Peter Control of the cell cycle through mechanisms involving ubiquitination
Kessenbrock, Kai Microenvironmental regulation of epithelial stem cell function in single cell resolution during normal tissue homeostasis and cancer
Keyak, Joyce Bone biomechanics and structural analysis; Effects of medications, aging, tumors, radiotherapy, and spaceflight on bone; Cancer and radiotherapy; Imaging using quantitative computed tomography
Kheradvar, Arash Cardiovascular engineering with emphasis on cardiac mechanics, cardiac imaging and cardiovascular devices
Khine, Michelle Biomedical engineering: microfluidics, molecular diganostics and stem cell technologies
Komarova, Natalia Mathematical biology: modeling of cancer initiation and progression,  dynamics of DNA transcription and repair, modeling of learning and evolution of language
Kruggel, Frithjof Signal and image processing for analysis of neurofunctional data (MRI, fMRI, PET, ERP, ERF), relation between structure and function in the human brain
Lander, Arthur Systems biology of growth control, morphogenesis and pattern formation; complex trait genetics; birth defects syndromes
Lanyi, Janos  Bacteriorhodopsin, spectroscopy, protein crystallography
Lathrop, Rick Artificial Intelligence: Automated Reasoning / Machine Learning / Data Mining / Bio-Medical Informatics / Computational Biology / Protein Structure Prediction / Drug Discovery / Genetic Regulation 
Lawson, Devon Cancer, metastasis, intratumor heterogeneity, single-cell omics, metastatic evolution
Lee, Eva Cell cycle and molecular genetics studies of breast cancer

Liu, Chang

Synthetic biology, chemical biology and directed evolution
Liu, Haoping MAP kinase mediated signal transduction; dimorphic regulation in yeast.
Liu, Wendy Biomedical engineering: nano-fabrication tools, protein engineering and HTS approaches for study of immue cell plasticity
Long, Anthony Quantitative and population genetics, genetic basis of quantitative variation for different phenotypes in different organisms, gene mapping and microarray analysis
Lowengrub, John Microstructured Materials, Multiphase Flows, Crystal Growth, Nanostructure Patterning, Metallic Alloys, Tumor Growth, Tissue Engineering
Luecke, Hartmut "Hudel" Protein crystallography, structure function studies, membrane proteins, bacteriorhodopsin, annexi, G protein-coupled receptors (GPCR), structure-based drug design
Luo, Ray Computational Biology, Protein Structure, Protein Function
Macciardi, Fabio Genetics of complex disorders: schizophrenia, bipolar disorder, autism and related disorders
Marsh, Larry Regulation of growth factor signaling in patterning, regeneration, and oncogenesis, Mechanisms of late onset neurodegeneration
Martens, Craig Theoretical Chemistry, Chemical Physics 
Martiny, Adam Microbiology, Environmental Genomics, Oceanography
McHenry, Matthew Biomechanics, Locomotion, Sensory Biology 
Mease, Kenneth Nonlinear dynamics, control and optimization
Mjolsness, Eric Artificial Intelligence: Automated Reasoning / Machine Learning / Data Mining / Bio-Medical Informatics / Computational Biology / Systems Biology / Scientific Inference Systems / Mathematical Methods
Monuki, Edwin Morphogen and transcription factor regulation of cell fates and boundaries in the developing forebrain
Mortazavi, Ali Applications of genomics, computation, and sequencing technologies to the analysis of transcriptional regulation in development. Emphasis on long-range protein-DNA interactions, ChIP-seq, RNA-seq, ChIA-PET, and comparative genomics
Mukamel, Shaul Theoretical studies of ultrafast dynamics and relaxation processes of large molecules, biological complexes, and semiconductors; Nonlinear ultrafast spectroscopy
Nenadic, Zoran Adaptive biomedical signal processing, control algorithms for biomedical devices, brain-machine interfaces, modeling and analysis of biological neural networks
Nguyen, Hung Self-assembly of biological and biomimetic nanoscale materials based on amino acids and on nucleic acids using computational and theoretical methods
Nie, Qing Computational Biology, Developmental and Cell Biology, Numerical Analsis, Interface Dynamics in Materials and Fluids, High-Performance Computing, Modeling and Simulation of Tissue Patterning, Systems Biology
Noymer, Andrew Demography; mathematical models of disease transmission at the population level; epidemiology; mathematical models of social phenomena.
Parker, Ian Cell Signaling
Pathak, Medha Mechanobiology of neural stem cells; How cells transduce mechanical forces; Mechanically-activated ion channels; Role of Piezo1 in neural stem cell fate; Mechanical forces in neural development.
Plikus, Maksim Stem cells and stem cell niche, regeneration of tissues and organs, biological pattern formation, self-organization, skin and hair follicles, adipose tissue, WNT and BMP signaling pathways
Potma, Eric Molecular Mobility in Biological Materials, Vibrational Coherences, Ultrafast Microscopy
Prescher, Jennifer Chemical biology, molecular imaging, organic chemistry, immunology, bioorthogonal chemistry, post-translational modifications  
Rafelski, Susanne Intracellular organization, geometry of organelles (size, shape, position, dynamics), mitochondrial networks
RanzJose  Structural evolutionary genomics and evolution of the expression network
Read, Elizabeth Computional and modeling approaches to the study of immune system dynamics and regulation
Ritz, Thorsten Biological physics, magnetic sense of animals, quantum biology of photosynthesis
Sandmeyer, Suzanne Molecular genetics and biochemistry of retrotransposons and metabolic engineering in budding yeast
Schilling, Tom Zebrafish development, pattern formation, morphogenesis
Shahbaba, Babak Developing Bayesian methods and applying them to real-world problems; applying novel statistical methods to solve research questions in genetics, genomics, proteomics, and cancer studies
Sheu, Phillip C-Y Database Systems, Object-Oriented Systems, Parallel Processing, Simulation, Interactive Multimedia Systems. Biomedical Database Management, Intranet/Internet Technologies
Shi, Yongsheng Genomics of post-transcriptional gene regulation, mRNA processing, cancer
Siryaporn, Albert Biomechanics, Bacterial Signaling, Bacterial Pathogenesis, Biofilms
Siwy, Zuzanna Experimental Biophysics, Condensed Matter Physics
Smyth, Padhraic Artificial Intelligence; Large-Scale Data Analysis; Statistics
Solna, Knut Applied mathematics, applied probablility, stochastic differential equations
Spanier, Jerome Mathematical modeling and computational methods; Monte Carlo methods; computational biophotonics; radiative transport and diffusion processes; biomedical optics
Stanford, Kyle History and philosophy of biology
Steele, Robert Molecular biology of Hydra development
Stern, Hal statistical inference using Bayesian methods, assessing the fit of statistical models, applications of statistics in the social and biological sciences, and statistics in sports.
Sun, Sha Genetic and epigenetic programing; functions of long range non-coding RNAs
Taborek, Peter surface physics, sensors, high speed imaging, and fluid mechanics
Tan, Ming  Gene Expression and Pathogenesis in Chlamydia Trachomatis
Thornton, Kevin Comparative genomics, Population Genetics, and statistical Genetics
Tobias, Douglas Computational Chemistry, Biophysical Chemistry, Atmospheric Chemistry
Tromberg, Bruce Lasers, near infrared spectroscopy, non-invasive diagnostics, photomedicine, biomedical optics, photodynamic therapy
Tsai, Sheryl Biochemistry, Chemical Biology, Structural Biology, Microbiology
Venugopalan, Vasan Biomedical laser applications, optical diffusion theory, photothermal and photomechanical phenomena
Wan, Frederic Y.M. Applied Mathematics, Solid Mechanics, Resource Economics, Biomathematics
Wang, Wenqi Hippo pathway, organ size control, cancer biology, and proteomics
Warrior, Rahul Drosophila development, regulation of nuclear position and migration, effects of proteoglycans in growth factor signaling, regulation of developmental gene expression.  
Waterman, Marian  Regulation of gene expression by LEF/TCF - beta-catenin complexes
Weiss, Gregory Bioorganic chemistry, chemical biology, protein engineering, molecular biology and biochemistry
Welling, Max Machine Learning and Intelligent Systems
Whiteson, Katrine Host-associated microbial communities, metabolomics, metagenomics, microbial ecology, microbial interactions, human microbiome
Wickramasinghe, Kumar Low Cost DNA Sequencing, Single Cell Omics, Microscopy and Spectroscopy on the Nanoscale
Wodarz, Dominik Mathematical and Computational Biology, Theoretical Biology, infectious diseases and the immune system, carcinogenesis & cancer treatment
Wu, Ruqian Quantum mechanical and molecular dynamics simulations for complex systems
Wunderlich, Zeba Experimental and computational approaches to studying the regulation of gene expression, Drosophila development, interpreting natural variation in regulatory sequences
Xie, Xiaohui Computational Biology, Bioinformatics, Genomics, Neural Computation, and Machine Learning
Xin, Jack Analysis and Modeling of Reaction-Diffusion-Advection Fronts, Stochastic Partial Differential Equations, Asymptotics and Computations, Multiscale Analysis of Partial Differential Equations and Applications, Mathematical Modeling in Speech and Hearing Sciences. 
Yokomori, Kyoko Mechanism and regulation of chromosome structural changes required for the maintenance of genome integrity
Yu, Clare Biological physics, Intracellular transport, Disordered systems
Yu, Zhaoxia Methods and computational tools to improve our understanding of genetic and environmental determinants of complex traits
Zhao, Hong-kai The Level Set Method, Moving Interface and Free Boundary, Image Processing and Computer Graphics, Time Reversal and Wave Propagation, Domain Decomposition
2011 Faculty. Copyright © 2013. The Center for Complex Biological Systems, UC Irvine
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