Chromatin Dynamics Interest Group

This month's "Chromatin Dynamics Interest Group" will be meeting tomorrow, Friday, May 22, 2015 from 2:00 - 3:00pm in Natural Sciences II, Rm 3201
 
Tomorrow's topic: "Spatial dynamics of SIRT1 dictate metabolic transitions in the cell nucleus."
Speaker: Suman Rangit and Lorena Aguiliar
 
Light refreshments will be provided.
 
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Metabolomics Interest Group (MIG)

This month's Metabolomics Interest Group meeting is scheduled for Tuesday, May 26th from 3:00 - 4:00 pm, BioSci III Conference Room, Rm 2120.
 

MosqCloudPlotThe MIG provides an informal venue for both current research groups, as well as new users, to i) more effectively utilize campus metabolomics resources, ii) obtain user support and provide community feedback, and iii) promote opportunities for collaborative interactions.

We will be discussing:
 
1) Processing of GC EI-MS data, specifically:
- Spectra deconvolution from complex mixtures
- Spectra searching of databases, e.g. NIST libraries
- Scoring match results and building user databases
 
2) Reviewing statistical methods for LC-MS/MS data:
- Processing peak lists for biomarker selection (normalization and parameter selection)
- Data plotting tools, including Cloud plots, Volcano plots, Heatmaps etc.
 
Please check back on the Community pages for future announcements or send an email to This email address is being protected from spambots. You need JavaScript enabled to view it. (Subj: MIG) to be included on the mailing list.
 
 

Metabolomics Interest Group (MIG)

The 2nd meeting of the Metabolomics Interest Group was held on:
 
Monday, April 20th from 1:00 - 2:00 pm
BioSci III Conference Room, Rm 2120.
 
The MIG provides an informal venue for both current research groups, as well as new users, to i) more effectively utilize campus metabolomics resources, ii) obtain user support and provide community feedback, and iii) promote opportunities for collaborative interactions.
 
This month's topic was on "Metabolite Biomarker Identification" from untargeted global mass spec data collected by GC EI-MS, LC-MS or MSMS instruments.
 
We reviewed:
      • Basic untargeted metabolomics experimental designs,
      • Sample handling and data collection 
      • Various software analytical packages, including: Waters MarkerLynx and Progenesis QI packages, Scripps XCMS Online and the open source package MetaboAnalyst.
 
 
Please check back on the Community pages for future announcements or send an email to This email address is being protected from spambots. You need JavaScript enabled to view it.  (Subj: MIG) to be included on the mailing list.
 
 

Metabolomics Interest Group (MIG)

A new interest group focused on "Metabolomics" will meet monthly. The MIG is intended as an informal venue for both current research groups, as well as new users, to i) more effectively utilize campus metabolomics resources, ii) obtain user support and provide community feedback, and iii) promote opportunities for collaborative interactions.
The aims of the Metabolomics Interest Group will be to cover:
    1. Advances in methods/technologies/instrumentation - primarily MS techniques.
    2. Strategies for small molecule quantification and biomarker identification.
    3. Data processing pipelines and software for manipulation of large omic datasets.
    4. Basic training for open access instruments in the UCI Mass Spectrometry Core Facility.
The meetings will be a mix of journal club format, short presentations on specific topics and training opportunities.
 
Our first meeting will be on Monday, Feb 23 @ 1:00 - 2:00 pm, in BioSci III, Rm 2120 (conference room).
Monday's topic: Targeted analyte quantitation by UPLC-MS/MS.
Demonstration: MS Core Facility, Waters Quattro Premier XE (triple quadropole MS). 
 
 
 

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Modeling and Theoretical Biology Interest Group

The next meeting of the "Modeling & Theoretical Biology Interest Group" (MTBIG) will be on Monday, March 9 from 3:30 - 4:30 pm in BioSci III, Rm 2622 (CCBS conference room).
 
Discussion leader: Abed Alnaif
 
Topic: Coordination of patterning and growth by morphogen gradients
 
Discussion Paper: "Coordination of progenitor specification and growth in mouse and chick spinal cord."
Anna Kicheva et al. Science (2014), 345, 1254927; DOI: 10.1126/science.
 
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